August 14, 2019
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Human clinical trials are using CRISPR/Cas9 to combat cancer and blood disorders. In these tests, researchers remove some of a person’s cells, edit the DNA and then inject the cells back in, now hopefully armed to fight disease. Researchers are …
March 26, 2019
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Base editing with reduced DNA nicking allows for the simultaneous editing of over 10,000 loci (13,000) in human cells. Performing this feat in the human genome will require the modification of 4438 Amber codons. They have shown that gene editors …
February 21, 2019
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CRISPR-Cas9 gene-editing system has made pluripotent stem cells that are functionally “invisible” to the immune system which will prevent rejection of stem cell transplants. Universal stem cells can be produced that will work for everyone and there will not be …
February 21, 2019
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Salk Institute researchers have used CRISPR/Cas9 therapy to suppress aging, enhance health and extend life span in mice. Above – This image shows two mice of the same age with progeria. The larger and healthier mouse on the left received …
January 15, 2019
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George Church describes going beyond cutting DNA to precise editing. 1. Phage Integrases (Protein and DNA) 2. TAL Deaminases (custom Protein) 3. Chemical Targeting (custom polymer) 4. lambda (λ)-red recombinase (Custom DNA) Beyond editing to writing large genomes DNA-based target …
January 11, 2019
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Kheiron Biotech using clones thoroughbred horses and announced in 2017 that they would use CRISPR gene editing to create super horses. They plan to perform myostatin inhibition to boost the muscles in horses. They will develop horses with more muscle …